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Amino acid symbols: Symbols that stand for the amino acids , the building blocks of protein . Each amino acid has both a three-letter symbol and a single-letter symbol. For example, the three-letter and single-letter symbols for alanine are Ala and A. The three-letter symbols (such as Ala) are much more widely used than the single letter ones (such as A). Therefore, the following list is limited to the three-letter symbols and is further limited to those 20 alpha-amino acids specified by the genetic code :

  • Alanine : Ala
  • Arginine : Arg
  • Asparagine : Asn
  • Aspartic acid : Asp
  • Cysteine : Cys
  • Glutamic acid : Glu
  • Glutamine : Gln
  • Glycine : Gly
  • Histidine : His
  • Isoleucine : Ile
  • Leucine : Leu
  • Lysine : Lys
  • Methionine : Met
  • Phenylalanine : Phe
  • Proline : Pro
  • Serine : Ser
  • Threonine : Thr
  • Tryptophan : Trp
  • Tyrosine : Tyr
  • Valine : Val

These three-letter symbols for amino acids are used not only to refer to an individual amino acid but also to present the amino acid sequence of a polypeptide or a protein. For example, part of the sequence of insulin reads: Gly-Ile-Val-Glu-Gln-Cys-Cys-Ala-Ser-Val. The N-terminal residue of the polypeptide or protein is by convention always on the left and the sequence reads from left-to-right toward the C-terminal residue of the polypeptide or protein.


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