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Annexin A1: One of the annexins , a family of proteins that share the property of binding calcium and phospholipids. The gene for annexin A1 (ANXA1) is upregulated in hairy cell leukemia . ANXA1 protein expression is specific to hairy cell leukemia. Detection of ANXA1 (by immunocytochemical means) reportedly provides a simple, highly sensitive and specific assay for the diagnosis of hairy cell leukemia.

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