APC: 1. Antigen-presenting cell . Among the APCs are dendritic cells.
2. Aspirin, phenacetin, and caffeine (a pill containing all three).
3. Adenomatous polyposis coli, a gene involved in both sporadic and familial colorectal cancer . Mutation in the APC gene is the earliest detectable molecular abnormality in colorectal cancer and imitates the process 20 to 30 years before the malignancy is full-blown. APC is a large gene that maps to chromosome 5 in region 5q21-q22. Although a number of different mutations have been identified in the APC gene, most (about 80%) of them cluster in one area of the gene, interrupt its transcription , and truncate (cut off) the transcript.

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