Basophil: A type of leukocyte ( white blood cell ) with coarse bluish-black granules of uniform size within the cytoplasm and typically a bilobate (two-lobed) nucleus . Basophils are so named because their cytoplasmic granules stain with basic dyes. Basophils normally constitute 0.5 to 3% of the peripheral blood leukocytes . Basophils contain (and can release) histamine and serotonin . Also called a basophilic leukocyte.

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