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Chromosome 1: The largest human chromosome , comprising approximately 10% of the human genome . Chromosome 1 contains over 240 million base pairs and over 3000 genes including the UROD gene for porphyria cutanea tarda , the GBA gene for Gaucher disease , the GLC1A gene for glaucoma , the HPC1 gene for prostate cancer , and the PS2 gene for Alzheimer disease .

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