Delirium: A sudden state of severe confusion and rapid changes in brain function, sometimes associated with hallucinations and hyperactivity , in which the patient is inaccessible to normal contact. Symptoms may include inability to concentrate and disorganized thinking evidenced by rambling, irrelevant, or incoherent speech. There may be a reduced level of consciousness, sensory misperceptions and illusions, disturbances of sleep, drowsiness, disorientation to time, place, or person, and problems with memory.

Delirium can be due to a number of conditions that derange brain metabolism , including infection, brain tumor , poisoning, drug toxicity or withdrawal, seizures, head trauma , and metabolic disturbances such as fluid, electrolyte , or acid-base imbalance, hypoxia , hypoglycemia , or hepatic or renal failure.

Also called acute confusional state and acute brain syndrome .

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