Disease, Jakob-Creutzfeldt: A transmissible degenerative brain disorder technically termed spongiform encephalopathy. Eating "mad cow" meat or squirrel brain can lead to Jakob-Creutzfeldt-like disease. Better known as Creutzfeldt-Jakob disease (CJD). A dementing disease of the brain, believed due to an unconventional, transmissible agent (a prion). Symptoms of CJD include forgetfulness, nervousness, jerky trembling hand movements, unsteady gait, muscle spasms, chronic dementia , balance disorder, and loss of facial expression. CJD is classified as a spongiform encephalopathy. Most cases occur randomly (sporadically), but inherited forms exist. There is neither treatment nor cure for CJD. Other names for CJD include Creutzfeldt-Jakob syndrome, Jakob's disease, and spastic pseudoparalysis.

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