Hepatic encephalopathy: Brain dysfunction directly due to liver dysfunction, most often recognized in advanced liver disease. Hepatic encephalopathy may cause disturbances of consciousness and progress to coma .

Hepatic encephalopathy is sometimes said to be synonymous with hepatic coma but this is incorrect. Hepatic coma is the end-stage of the process.

In minimal hepatic encephalopathy (MHE), there may be subtle impairment of behavior, intelligence, and neuromuscular function. Driving ability in MHE may be diminished.

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