Hyperemesis gravidarum: Excessive vomiting in early pregnancy. Hyperemesis gravidarum, by definition, leads to the loss of 5% or more of the body weight of the woman.

Hyperemesis gravidarum affects about one in every 300 pregnant women. It is more common in young women, in first pregnancies and in women with multiple pregnancies (twins, triplets, etc.)

Hyperemesis gravidarum is usually self-limited (stops on its own) and, although very inconvenient and very discomforting, it is usually of little clinical consequence. However, sometimes hyperemesis can keep the mother from getting the necessary fluids and nutrition.

Some women with hyperemesis gravidarum have high concentrations of the hormones hCG (human chorionic gonadotropin), estrogen, or thyroid hormone in the blood. A few of them also have clinical manifestations of hyperthyroidism (over-active thyroid state).

The treatment of mild hyperemesis gravidarum is usually with dietary measures, rest and antacids. Very severe hyperemesis gravidarum may call for intravenous fluid and nutrition.

Hyperemesis gravidarum is the medical name for excessive vomiting in pregnancy. Hyper means "over"; emesis means "vomiting"; gravidarum means "pregnant state."

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