Integron: A mobile DNA element that can capture and carry genes, particularly those responsible for antibiotic resistance . Integrons do this by site-specific recombination .
There are at least three classes of integrons based upon which integrase gene they contain. The antibiotic resistance genes that integrons capture are located on gene cassettes . These cassettes can exist as free circular DNA. A recombination event occurs, integrating the cassette into the integron. Additional gene cassettes can integrate, resulting in the integration of several genes.
Although gene cassettes are a mechanism for the development of multiple antibiotic resistance, bacteria predating the use of antibiotics have also been found to contain cassettes.
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