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Keshan disease: Condition caused by deficiency of the essential mineral selenium. Keshan disease is a potentially fatal form of cardiomyopathy (disease of the heart muscle). It was first observed in Keshan province in China and since has been found elsewhere (including New Zealand and Finland) in areas where the selenium level in the soil is low. Treatment is selenium supplementation. The recommended dietary allowance (RDA) is currently 55 micrograms of selenium per day for adult men and women, 60 micrograms per day for women during pregnancy and 70 micrograms per day for women during lactation.


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