Lumen: A luminous term referring to the channel within a tube such as a blood vessel or to the cavity within a hollow organ such as the intestine . Lumen is a luminous term because it is Latin for light, including the light that comes through a window. When a hollow organ is cut across, you can see light through the space that has been opened. So the word "lumen" came to mean this space.

For example, in arteriosclerosis , fat deposits narrow the lumen of the artery. For another example, cells called enetrocytes within the intestinal wall help transport water from the lumen of the intestine into the bloodstream.

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