Lung reduction surgery: A surgical treatment for patients with advanced emphysema in which 20-35% of the emphysematous lung is removed to allow the remaining tissue to expand more fully and restore some of the patient's breathing capacity. Also called lung-volume-reduction surgery. When this surgery is successful, there is improvement in lung function, exercise capacity, and the quality of life. However, the surgical mortality rate is appreciable (4 to 15%, according to the particular study). In a meticulous study, the National Emphysema Treatment Trial Research Group found that lung reduction surgery is detrimental to patients with the most severe emphysema -- those with severe injury to blood vessels of the lung and those with empysema distributed uniformly throughout their lungs. Surgery for emphysema is not for everyone.

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