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Mercaptopurine: A drug that acts as an antimetabolite , interfering with the metabolism of purine bases and inhibiting the synthesis of DNA and RNA .

Mercaptopurine is used to treat acute lymphoblastic leukemia, acute myeloid leukemia ( AML ), and polycythemia vera . It is also used in the treatment of Crohn's disease , ulcerative colitis , and psoriatic arthritis .

Also known as 6-mercaptopurine, 6-MP, or MP.

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