GENERIC NAME: cefdinir

BRAND NAME: Omnicef

DRUG CLASS AND MECHANISM: Cefdinir is a semi-synthetic (partially man-made) oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefixime (Suprax), cefprozil and many injectable antibiotics. Cefdinir is active against a very wide spectrum of bacteria, including: Staphylococcus. aureus, Streptococcus. pneumoniae, Streptococcus pyogenes (the cause of strep throat ), Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis. Compared to cefixime, it is more active against Staph and Strep, but less active against Hemophilus and Klebsiella. It is not active against Pseudomonas. Therapeutic uses of cefdinir include otitis media , soft-tissue infections, and respiratory tract infections. It was approved by the FDA in December of 1997.

GENERIC AVAILABLE: no

PRESCRIPTION: yes

PREPARATIONS: Capsules: 300mg (lavender and turquoise); oral suspension (strawberry flavored), 125mg per teaspoonful in 60mL and 100mL containers.

STORAGE: Capsules should be stored at room temperature, between 15-30 °C (59-86 °F).

PRESCRIBED FOR: Cefdinir is effective against susceptible bacteria causing infections of the middle ear (otitis media), tonsils (tonsillitis), throat, larynx (laryngitis), bronchi (bronchitis, lungs ( pneumonia ), and skin and soft tissue.

DOSING: Cefdinir is taken once or twice daily, depending on the nature and severity of the infection. The capsules or suspension can be taken with or without food. Patients with advanced renal diseases may need to take lower doses.

DRUG INTERACTIONS: There are no known clinically important drug interactions with cefdinir.

PREGNANCY: There are no adequate studies of cefdinir in pregnant women. However, studies in animals suggest no important effects on the fetus. Cefdinir therefore can be used in pregnancy if the physician feels that it is necessary.

NURSING MOTHERS: It is not known if cefdinir is secreted in breast milk.

SIDE EFFECTS: Cefdinir generally is well tolerated. The most common side effects are diarrhea or loose stools, nausea, abdominal pain , and vomiting, each of which may occur in fewer than one in thirty persons who receive the drug. Rarer side effects include abnormal liver tests and allergic reactions. Cefdinir may cause false test results with some urine sugar tests.

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