GENERIC NAME: cefuroxime

BRAND NAME: Ceftin

DRUG CLASS AND MECHANISM: Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. It is effective against a wide variety of bacteria organisms, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhoeae, and many others.

PRESCRIPTION: yes

GENERIC AVAILABLE: yes

PREPARATIONS: Tablets: 125 mg, 250 mg, 500 mg. Suspension: 125 mg per 5 ml teaspoon.

STORAGE: Tablets should be stored at room temperature in a tightly closed container. The oral suspension should be stored in the refrigerator in a tightly closed container.

PRESCRIBED FOR: Cefuroxime is effective against susceptible bacterias causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, and pneumonia . It is also used in treating urinary tract infections, skin infections, and gonorrhea. Additionally, it is useful in treating acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).

DOSING: Should be taken with food.

DRUG INTERACTIONS: Cefuroxime should be avoided by patients with a known allergy to cephalosporin type antibiotics. Since cefuroxime is chemically related to penicillin, an occasional patient can have an allergic reaction (sometimes even anaphylaxis ) to both medications. Treatment with cefuroxime and other antibiotics can alter the normal bacteria flora of the colon and permit overgrowth of C. difficile, a bacteria responsible for pseudomembranous colitis. Patients who develop pseudomembranous colitis as a result of antibiotics treatment can experience diarrhea , abdominal pain , fever, and sometimes even shock. Probenecid may increase the blood levels of cefuroxime. Cefuroxime can be used by children. It is not habit forming.

SIDE EFFECTS: Cefuroxime is generally well tolerated and side effects are usually transient. Reported side effects include diarrhea, nausea, vomiting, abdominal pain, headache, rash, hives , vaginitis, headache, and mouth ulcers.

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