GENERIC NAME: doxazosin mesylate

BRAND NAME: Cardura

DRUG CLASS AND MECHANISM: Cardura is an inhibitor of the alpha 1 adrenergic nervous system. Elevated blood pressure (hypertension) is lowered as the action of these nerves, which promote constriction of blood vessels, is blocked.

Cardura was also found to relax the muscles around the prostate gland which is also under the influence of the alpha adrenergic portion nervous system. This can makes urination easier for men affected by enlarged prostate glands.

PRESCRIPTION: yes

GENERIC AVAILABLE: yes

PREPARATIONS: 1mg, 2mg, 4mg, and 8mg oral tablets.

STORAGE: Store in a dry place at 30 degrees C (86 F).

PRESCRIBED FOR: Cardura is used for the control of elevated blood pressure (hypertension) and for benign prostatic hyperplasia (noncancerous enlargement of the prostate gland).

DOSING: Cardura should be taken at doses specifically directed by your physician. This medication can be taken with or without food. Cardura should be taken the same time each day to maintain proper blood levels. Do not take Cardura within two hours of taking an antacid. If stopped you must taper the dose.

DRUG INTERACTIONS: Do not use in excess. First doses of Cardura or any Alpha 1 inhibitor should be taken with caution. The first doses may cause excessive lowering of the blood pressure and cause dizziness and fainting . Strict compliance with dosing is mandatory. Usually a slow increase in dosing is desirable.

PREGNANCY: This medication should be taken while pregnant only if strongly indicated.

SIDE EFFECTS: An uncommon but dangerous side effect is a drop in the white blood cells which normally help to fight infection. Liver damage is uncommon. Dizziness and fainting can occur if the blood pressure is lowered too fast. Swelling of the ankles and fatigue may occur. Most persons should have periodic blood studies while taking Cardura. This medication will rarely cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion and sexual dysfunction. Consult your pharmacist and physician for additional drug interactions.

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