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GENERIC NAME: fluconazole

BRAND NAME: Diflucan

DRUG CLASS AND MECHANISM: Antifungal (treatment of certain fungus infections).

PRESCRIPTION: yes

GENERIC AVAILABLE: yes

PREPARATIONS: Suspension content per bottle is 350mg (when diluted 10mg per ml) and 1400mg (when diluted 40mg per ml). Tablets are available in 50mg, 100mg, and 200mg from Roerig Labs. Intravenous solutions are available.

STORAGE: Store tablets in a dry place at 20-25 degrees C (68-77 F), oral suspensions after dilution at 5-30 degrees C (41-86 F) the oral suspension should be discarded in 2 weeks after reconstituted.

PRESCRIBED FOR: Oral, esophageal, urinary, vaginal and possibly other organ infections caused by the fungus Candida. Fluconazole has also been used in the fungal infection Cryptococcus.

DOSING: Fluconazole is taken orally or by intravenous injection. Modified dosing is needed if the patient has impaired renal function or if taking certain other medications at the same time. Please consult your pharmacist or physician if taking other medications with fluconazole. This drug can be used in children and has been effective down to the age of 6 months of age. Fluconazole can cause liver damage in rare cases and the liver should be monitored if taken for several days.

DRUG INTERACTIONS: Caution if taking certain other medications with fluconazole such as phenytoin, cyclosporin, theophylline and coumadin. If a rash occurs while taking this medication notify your doctor.

PREGNANCY: Use of fluconazole in pregnancy is not usually recommended.

NURSING MOTHERS: Use of fluconazole in nursing mothers is not usually recommended.

SIDE EFFECTS: The incidence of side effects from this medication is relatively high (up to 25%) Many (13%) may get headaches. Some patients develop nausea, abdominal pain , diarrhea or dizziness . Severe skin rash may occur but is uncommon.

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