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Pharmacy Author: Omudhome Ogbru, Pharm.D.
Medical Editor: Jay Marks, M.D.

GENERIC NAME: pentosan

BRAND NAME: Elmiron

DRUG CLASS AND MECHANISM: Pentosan is a semi-synthetic (man-made) drug used for treating the symptoms of interstitial cystitis . Interstitial cystitis is a condition, usually of unknown cause, in which there is inflammation of the bladder that most frequently causes pelvic pain and frequent urination. The exact mechanism whereby pentosan reduces the symptoms of interstitial cystitis also is unknown; however, scientists believe that pentosan may coat the lining of the bladder and prevent irritating substances in the urine from reaching the cells of the lining.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Capsules: 100 mg.

STORAGE: Store at room temperature between 15-30°C (59-86°F).

PRESCRIBED FOR: Pentosan is used for relieving bladder pain caused by interstitial cystitis.

DOSING: The recommended dose of pentosan is 100 mg three times daily. The effect of food on absorption of pentosan is unknown, and, therefore, it should be taken at least one hour before or two hours after meals so that food cannot retard its absorption.

DRUG INTERACTIONS: Drug interaction studies have not been conducted with pentosan.

PREGNANCY: Studies with pentosan have not been conducted in pregnant women.

NURSING MOTHERS: Studies of pentosan have not been conducted in nursing mothers.

SIDE EFFECTS: The most common side effects of pentosan are stomach upset, diarrhea , nausea, headache , rash , abdominal pain , hair loss and dizziness. Some patients may abnormalities of liver tests in the blood.

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