GENERIC NAME: potassium chloride

BRAND NAMES: K-Dur, K-Lor, K-Tab, Kaon CL, Klorvess, Slow-K, Ten-K, Klotrix, K-Lyte CL

DRUG CLASS AND MECHANISM: Potassium chloride is in the class of drugs called potassium supplements which are used to treat low potassium conditions (hypokalemia) or prevent them from occurring. Potassium is the principal positive ion inside of the cells of the body and is used in nerve conduction, muscle contraction, and normal kidney function. A deficiency of potassium causes weakness, fatigue, heart rhythm problems, paralysis, and kidney dysfunction.

PRESCRIPTION: yes

GENERIC AVAILABLE: yes

PREPARATIONS: Tablets and capsules; 8 mEq, 10 mEq, 20mEq. Slow-K 8 mEq extended-release tablets; Powder and liquid also available.

STORAGE: Potassium should be stored at room temperature in a tight container.

PRESCRIBED FOR: Low potassium conditions (hypokalemia) occur when the amount of potassium lost in the kidneys or intestines exceeds the amount of potassium taken in. This usually occurs slowly with the use of diuretics. However, it can also occur in diabetic ketoacidosis, severe diarrhea , conditions wherein the patient is receiving IV fluids and not eating, and rare disorders of the adrenal glands. Potassium chloride is used to treat hypokalemia and to prevent hypokalemia from occurring when strong diuretics are used. Potassium can also be used to treat digitalis toxicity.

DOSING: Potassium is usually taken with meals and fluids to prevent intestinal problems.

DRUG INTERACTIONS: Cardiac arrest can occur with high potassium conditions, such as chronic renal failure, burns , acidosis, dehydration , and potassium sparing diuretic usage. Potassium supplements should not be given to these patients. Ulcers and bleeding can occur in patients with intestinal problems, especially those who are taking slow- release tablets. Drug interactions causing elevation of potassium can occur with ACE inhibitors (used to treat high blood pressure ) and certain diuretics (aldactone and triamterene). Blood tests to measure potassium levels should be followed regularly in these patients. Slow-release tablets should be swallowed, not chewed or crushed.

SIDE EFFECTS: Severe side effects include high potassium and intestinal bleeding, ulceration, and perforation as mentioned above in

DRUG INTERACTIONS. More common reactions include nausea, vomiting, diarrhea, and abdominal pain .

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